Found this via
[Don Park's Daily Habit], and checked: it also works for Windows 2000 -
How to replace Notepad.exe on Windows XP/2000
Windows XP/2000 has file protection so Notepad.exe will get restored if you just replace the file with renamed Sc1.exe. Follow these steps:
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Save a copy of the original Notepad.exe somewhere.
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Replace Notepad.exe in following three locations (order is significant):
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%WINDIR%\ServicePackFiles\i386 (if any SP is installed)
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%WINDIR%\System32\DllCache
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%WINDIR%\System32
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%WINDIR%
*%WINDIR% is your Windows folder (i.e. C:\Windows)
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Press Cancel when a warning dialog appears.
That's it. Enjoy.
Update: have a look at simonguest's post how to get that work on Vista too.